Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 20/20 | 0.76 |
| ▸ | ACE | P12821 | 9/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14891056 | 1.00 | MME (0.76) | MMEACE | |
| SCHEMBL20681853 | 0.88 | MME (0.58) | MMEACE | |
| SCHEMBL15468114 | 0.88 | MME (0.58) | MMEACE | |
| SCHEMBL19753757 | 0.87 | MME (1.00) | MMEACE | |
| SCHEMBL14891224 | 0.87 | MME (1.00) | MMEACE | |
| SCHEMBL14900586 | 0.87 | MME (1.00) | MMEACE | |
| SCHEMBL19705881 | 0.84 | MME (0.62) | MMEACE | |
| SCHEMBL18012898 | 0.84 | MME (0.62) | MMEACE | |
| SCHEMBL19875571 | 0.81 | MME (0.56) | MMEACE | |
| SCHEMBL11969610 | 0.81 | MME (0.56) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773335-B1 | OXALIC ACID AMIDES AS NEPRILYSIN INHIBITORS, PHARMACEUTICAL COMPOSITION THEREOF AND PREPARATION THEREOF | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2017-03-08 | — | — | EP | disclosed |