Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 19/20 | 1.00 |
| ▸ | ACE | P12821 | 11/20 | 1.00 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14890855 | 1.00 | MME (1.00) | MMEACEMMEL1 | |
| SCHEMBL14891211 | 0.90 | MME (0.82) | MMEACEMMEL1 | |
| SCHEMBL18597739 | 0.90 | MME (0.82) | MMEACEMMEL1 | |
| SCHEMBL16011776 | 0.90 | MME (0.82) | MMEACEMMEL1 | |
| SCHEMBL18597981 | 0.89 | MME (1.00) | MMEACEMMEL1 | |
| SCHEMBL14890581 | 0.89 | MME (1.00) | MMEACEMMEL1 | |
| SCHEMBL14891190 | 0.89 | MME (0.80) | MMEACEMMEL1 | |
| SCHEMBL18597964 | 0.89 | MME (0.79) | MMEACEMMEL1 | |
| SCHEMBL14890436 | 0.89 | MME (0.79) | MMEACEMMEL1 | |
| SCHEMBL14890894 | 0.88 | MME (0.78) | MMEACEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773335-B1 | OXALIC ACID AMIDES AS NEPRILYSIN INHIBITORS, PHARMACEUTICAL COMPOSITION THEREOF AND PREPARATION THEREOF | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2017-03-08 | — | — | EP | disclosed |