Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18598177 | 1.00 | HTT (0.31) | HTTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL25664676 | 0.92 | HTT (0.33) | HTT | |
| SCHEMBL29610558 | 0.92 | HTT (0.33) | HTT | |
| SCHEMBL25664690 | 0.92 | HTT (0.33) | HTT | |
| SCHEMBL2601398 | 0.78 | DPP4 (0.39) | — | |
| SCHEMBL4758300 | 0.72 | — | — | |
| SCHEMBL15316993 | 0.72 | — | — | |
| SCHEMBL24121374 | 0.71 | DPP4 (0.44) | — | |
| SCHEMBL2601399 | 0.71 | DPP4 (0.44) | — | |
| SCHEMBL20748227 | 0.70 | HTT (0.35) | HTTCHRM5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326616-B1 | PROCESS FOR THE SYNTHESIS OF EZETIMIBE AND INTERMEDIATES USEFUL THEREFORE | LEK PHARMACEUTICALS (SI) | 2017-03-08 | — | — | EP | disclosed |