Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1859299 | 0.85 | CHRM3 (0.37) | CHRM4CHRM3 | |
| SCHEMBL1855721 | 0.83 | ATM (0.31) | — | |
| SCHEMBL1856554 | 0.82 | CHRM4 (0.32) | CHRM4CHRM3 | |
| SCHEMBL1860650 | 0.78 | KDM4E (0.31) | CHRM4CHRM3 | |
| SCHEMBL1856576 | 0.73 | BCHE (0.35) | — | |
| SCHEMBL1362081 | 0.72 | S1PR5 (0.41) | — | |
| SCHEMBL689996 | 0.72 | — | — | |
| SCHEMBL1854797 | 0.72 | — | — | |
| SCHEMBL1860026 | 0.68 | CHRM3 (0.35) | CHRM4CHRM3 | |
| SCHEMBL17977290 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863475-B1 | NOVEL THIOPHENE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE-1 RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-09-07 | — | — | EP | claimed |
| EP-1863787-B1 | HYDOGRENATED BENZO[C]THIOPHENE DERIVATIVES AS IMMUNOMODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-05-25 | — | — | EP | claimed |
| EP-1863474-B1 | NOVEL THIOPHENE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE-1 RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-11-12 | — | — | EP | claimed |