Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 6/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18601634 | 1.00 | CCR1 (0.34) | CCR1MCHR1KCNH2CCR2UBE2M | |
| SCHEMBL5487866 | 0.85 | CCR1 (0.33) | CCR1MCHR1KCNH2 | |
| SCHEMBL5487869 | 0.85 | CCR1 (0.33) | CCR1MCHR1KCNH2 | |
| SCHEMBL1323470 | 0.83 | CCR1 (0.35) | CCR1MCHR1KCNH2 | |
| SCHEMBL1323469 | 0.83 | CCR1 (0.35) | CCR1MCHR1KCNH2 | |
| SCHEMBL1323821 | 0.82 | CCR1 (0.35) | CCR1 | |
| SCHEMBL1323820 | 0.82 | CCR1 (0.35) | CCR1 | |
| SCHEMBL6362657 | 0.80 | CCR1 (0.38) | CCR1KCNH2 | |
| SCHEMBL656376 | 0.79 | CCR1 (0.57) | CCR1MCHR1UBE2MDCUN1D1 | |
| SCHEMBL656375 | 0.79 | CCR1 (0.57) | CCR1MCHR1UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688418-B1 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARM INC (US) | 2017-03-15 | — | — | EP | disclosed |