Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.35 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19336965 | 0.84 | EGFR (0.48) | EGFRKCNH2ALKEML4MLNR | |
| SCHEMBL19337022 | 0.83 | EGFR (0.47) | EGFRKCNH2ALKEML4MLNR | |
| SCHEMBL18607340 | 0.77 | EGFR (0.49) | EGFRKCNH2ALKEML4MLNR | |
| SCHEMBL17683113 | 0.77 | EGFR (0.60) | EGFRKCNH2ALKEML4MLNR | |
| SCHEMBL30459829 | 0.77 | EGFR (0.60) | EGFRKCNH2ALKEML4MLNR | |
| SCHEMBL17683231 | 0.77 | EGFR (0.60) | EGFRKCNH2ALKEML4MLNR | |
| SCHEMBL17683085 | 0.76 | EGFR (0.62) | EGFRKCNH2ALKEML4MLNR | |
| SCHEMBL18607355 | 0.75 | EGFR (0.59) | EGFRKCNH2ALKEML4MLNR | |
| SCHEMBL19254834 | 0.75 | EGFR (0.50) | EGFRKCNH2ALKEML4MLNR | |
| SCHEMBL18607059 | 0.75 | EGFR (0.48) | EGFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017035753-A1 | 2-ARYLAMINO PYRIDINE, PYRIDINE OR TRIAZINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 无锡双良生物科技有限公司 | 2017-03-09 | — | — | WO | disclosed |