Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 18/20 | 0.64 |
| ▸ | CHIT1 | Q13231 | 17/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.64 |
| ▸ | CHI3L1 | P36222 | 10/20 | 0.64 |
| ▸ | CHI3L2 | Q15782 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18608039 | 1.00 | CHIA (0.64) | CHIACHIT1KCNH2CHI3L1CHI3L2 | |
| SCHEMBL23169726 | 1.00 | CHIA (0.64) | CHIACHIT1KCNH2CHI3L1CHI3L2 | |
| SCHEMBL18589433 | 1.00 | CHIA (0.64) | CHIACHIT1KCNH2CHI3L1CHI3L2 | |
| Hydrochloric Acid SCHEMBL18577247 | 0.99 | CHIA (0.63) | CHIACHIT1KCNH2CHI3L1CHI3L2 | |
| Hydrochloric Acid SCHEMBL23143292 | 0.98 | CHIA (0.62) | CHIACHIT1KCNH2CHI3L1CHI3L2 | |
| Hydrochloric Acid SCHEMBL23143245 | 0.98 | CHIA (0.62) | CHIACHIT1KCNH2CHI3L1CHI3L2 | |
| SCHEMBL22903579 | 0.89 | KCNH2 (0.61) | CHIACHIT1KCNH2CHI3L1CHI3L2 | |
| SCHEMBL22901906 | 0.89 | KCNH2 (0.61) | CHIACHIT1KCNH2CHI3L1CHI3L2 | |
| Hydrochloric Acid SCHEMBL28703098 | 0.88 | KCNH2 (0.60) | CHIACHIT1KCNH2CHI3L1CHI3L2 | |
| SCHEMBL26223461 | 0.88 | CHIA (0.51) | CHIACHIT1KCNH2CHI3L1CHI3L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041726-A1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2 S,5 S)-5-(4-CHLOROBENZYL)-2-METHYLMORPHOLINO)PIPERIDIN-1-YL)-1 H-1,2,4-TRIAZOL-3-AMINE | Molecure SA (PL) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021059220-A1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2 S,5 S)-5-(4-CHLOROBENZYL)-2-METHYLMORPHOLINO)PIPERIDIN-1-YL)-1 H-1,2,4-TRIAZOL-3-AMINE | Oncoarendi Therapeutics S.A. (PL) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021059220-A1 | PROCESS FOR THE PRODUCTION OF 5-(4-((2 S,5 S)-5-(4-CHLOROBENZYL)-2-METHYLMORPHOLINO)PIPERIDIN-1-YL)-1 H-1,2,4-TRIAZOL-3-AMINE | Oncoarendi Therapeutics S.A. (PL) | 2021-04-01 | — | — | WO | disclosed |
| EP-3344616-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-01-09 | — | — | EP | disclosed |
| WO-2017037670-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2017-03-09 | — | — | WO | disclosed |