Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19337150 | 0.93 | EGFR (0.69) | EGFR | |
| SCHEMBL18610609 | 0.92 | EGFR (0.63) | EGFR | |
| SCHEMBL18610542 | 0.92 | EGFR (0.63) | EGFR | |
| SCHEMBL18610543 | 0.92 | EGFR (0.62) | EGFR | |
| SCHEMBL18586074 | 0.92 | EGFR (0.64) | EGFR | |
| SCHEMBL18610669 | 0.91 | EGFR (0.66) | EGFR | |
| SCHEMBL18610336 | 0.91 | EGFR (0.61) | EGFR | |
| SCHEMBL18610676 | 0.90 | EGFR (0.62) | EGFR | |
| SCHEMBL18610544 | 0.90 | EGFR (0.65) | EGFR | |
| SCHEMBL18610335 | 0.89 | EGFR (0.61) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017036263-A1 | 2, 4-DI-(NITROGEN CONTAINING GROUP) SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | 广州科擎新药开发有限公司 | 2017-03-09 | — | — | WO | disclosed |