Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 10/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1944678 | 0.89 | FYN (0.51) | FYNF2RL3TP53MAPTMEN1 | |
| SCHEMBL1943616 | 0.84 | FYN (0.47) | FYNNPC1RAB9AF2RL3TP53 | |
| SCHEMBL1650491 | 0.83 | MAPT (0.53) | FYNNPC1RAB9AF2RL3MAPT | |
| SCHEMBL1943656 | 0.83 | FYN (0.50) | FYNNPC1RAB9AF2RL3TP53 | |
| SCHEMBL1946744 | 0.83 | FYN (0.56) | FYNNPC1RAB9AF2RL3MAPT | |
| SCHEMBL1946328 | 0.82 | TP53 (0.47) | FYNNPC1RAB9AF2RL3TP53 | |
| SCHEMBL1945315 | 0.82 | MAPT (0.53) | FYNNPC1RAB9AF2RL3TP53 | |
| SCHEMBL1943707 | 0.82 | FYN (0.64) | FYNNPC1RAB9AF2RL3TP53 | |
| SCHEMBL1945978 | 0.81 | FYN (0.47) | FYNF2RL3TP53MAPT | |
| SCHEMBL1946837 | 0.81 | MKNK1 (0.57) | NPC1RAB9AF2RL3TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347462-A1 | METHODS, COMPOSITIONS, AND USES OF NOVEL FYN KINASE INHIBITORS | Lau, Warren C. (US) | 2018-07-18 | — | — | EP | claimed |
| WO-2017044623-A1 | METHODS, COMPOSITIONS, AND USES OF NOVEL FYN KINASE INHIBITORS | LAU WARREN C (US) | 2017-03-16 | — | — | WO | claimed |