Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.33 |
| ▸ | PRKCG | P05129 | 2/20 | 0.33 |
| ▸ | PRKCB | P05771 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | PRKCH | P24723 | 2/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040406 | 0.98 | TYR (0.43) | TYRABHD16APPARGNFKB1NFKB2 | |
| SCHEMBL18614676 | 0.98 | TYR (0.43) | TYRABHD16APPARGNFKB1NFKB2 | |
| SCHEMBL18614665 | 0.98 | TYR (0.43) | TYRABHD16APPARGNFKB1NFKB2 | |
| SCHEMBL2040408 | 0.98 | TYR (0.43) | TYRABHD16APPARGNFKB1NFKB2 | |
| SCHEMBL18614686 | 0.98 | TYR (0.43) | TYRABHD16APPARGNFKB1NFKB2 | |
| SCHEMBL18614711 | 0.98 | TYR (0.43) | TYRABHD16APPARGNFKB1NFKB2 | |
| SCHEMBL18614664 | 0.98 | TYR (0.43) | TYRABHD16APPARGNFKB1NFKB2 | |
| SCHEMBL20561501 | 0.98 | TYR (0.43) | TYRABHD16APPARGNFKB1NFKB2 | |
| SCHEMBL20561502 | 0.98 | TYR (0.43) | TYRABHD16APPARGNFKB1NFKB2 | |
| SCHEMBL2022983 | 0.98 | TYR (0.43) | TYRABHD16APPARGNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180334571-A1 | WATER REPELLENT COMBINATIONS | JANSSEN PHARMACEUTICA NV (BE) | 2018-11-22 | — | — | US | disclosed |
| EP-3347421-A1 | WATER REPELLENT COMBINATIONS | Janssen Pharmaceutica N.V. (BE) | 2018-07-18 | — | — | EP | disclosed |
| WO-2017042120-A1 | WATER REPELLENT COMBINATIONS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-16 | — | — | WO | disclosed |