Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 19/20 | 0.87 |
| ▸ | MERTK | Q12866 | 19/20 | 0.87 |
| ▸ | FLT3 | P36888 | 1/20 | 0.83 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18579594 | 1.00 | AXL (0.87) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18579849 | 0.96 | AXL (0.94) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18580134 | 0.94 | AXL (0.84) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18580177 | 0.94 | AXL (0.90) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18579890 | 0.93 | AXL (0.83) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18579850 | 0.93 | AXL (0.83) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18579696 | 0.93 | AXL (0.97) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18580382 | 0.93 | AXL (0.88) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18591608 | 0.93 | AXL (0.88) | AXLMERTKFLT3TYRO3 | |
| SCHEMBL18580176 | 0.93 | MERTK (1.00) | AXLMERTKFLT3TYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017039331-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2017-03-09 | — | — | WO | disclosed |