SCHEMBL186167

SCHEMBL186167

Cc1ncc(C(=O)O)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9653796 0.98 HCAR2 (0.96)
SCHEMBL27858708 0.84 HCAR2 (0.72)
SCHEMBL13451803 0.83 HCAR2 (0.70)
SCHEMBL4781387 0.82
SCHEMBL1107386 0.81 HCAR2 (0.68)
SCHEMBL1435803 0.80
SCHEMBL328096 0.80
Hydrochloric Acid SCHEMBL31078491 0.78 HCAR2 (0.64)
SCHEMBL12277009 0.78
Hydrochloric Acid SCHEMBL29217424 0.78 HCAR2 (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113943263-B Synthesis method of 2- (aminomethyl) -1, 3-thiazole-5-carboxylic acid methyl ester 凯美克(上海)医药科技有限公司 2025-03-21 CN claimed
US-20250084074-A1 SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS MERCK PATENT GMBH (DE) 2025-03-13 US claimed
CN-119265552-A Chemical nickel-plating palladium-gold solution 生益电子股份有限公司 2025-01-07 CN claimed
CN-110167944-B Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors 联合疗法公司 2024-08-23 CN claimed
EP-3672952-B1 BENZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS MERCK PATENT GMBH (DE) 2022-12-14 EP claimed
EP-3661941-B1 THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS MERCK PATENT GMBH (DE) 2022-12-14 EP claimed
US-20220306588-A1 BEZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS MERCK PATENT GMBH (DE) 2022-09-29 US claimed
US-11453647-B2 Benzimidazole derivatives as adenosine receptor antagonists MERCK PATENT GMBH (DE) 2022-09-27 US claimed
US-11192899-B2 Quinoxaline derivatives as adenosine receptor antagonists MERCK PATENT GMBH (DE) 2021-12-07 US claimed
US-11186592-B2 Thiazolopyridine derivatives as adenosine receptor antagonists MERCK PATENT GMBH (DE) 2021-11-30 US claimed
US-20150225450-A1 BENZYLAMINE DERIVATIVES AS INHIBITORS OF PLASMA KALLIKREIN KALVISTA PHARMACEUTICALS LTD (GB) 2015-08-13 US claimed
US-20150203534-A1 FLUORINATED EPOXYKETONE-BASED COMPOUNDS AND USES THEREOF AS PROTEASOME INHIBITORS FLUORINOV PHARMA INC. (CA) 2015-07-23 US claimed
EP-2885314-A1 FLUORINATED EPOXYKETONE-BASED COMPOUNDS AND USES THEREOF AS PROTEASOME INHIBITORS Fluorinov Pharma Inc. (CA) 2015-06-24 EP claimed
US-9051249-B2 Benzylamine derivatives as inhibitors of plasma kallikrein KALVISTA PHARMACEUTICALS LIMITED (GB) 2015-06-09 US claimed
WO-2014108685-A1 PHARMACEUTICAL COMPOSITIONS KALVISTA PHARMACEUTICALS LIMITED (GB) 2014-07-17 WO claimed
EP-2729443-A1 BENZYLAMINE DERIVATIVES AS INHIBITORS OF PLASMA KALLIKREIN Kalvista Pharmaceuticals Limited (GB) 2014-05-14 EP claimed
CN-103687846-A Benzylamine derivatives as inhibitors of plasma kallikrein KALVISTA PHARMACEUTICALS LTD 2014-03-26 CN claimed
WO-2014026282-A1 FLUORINATED EPOXYKETONE-BASED COMPOUNDS AND USES THEREOF AS PROTEASOME INHIBITORS SLASSI ABDELMALIK (CA) 2014-02-20 WO claimed
WO-2013005045-A1 BENZYLAMINE DERIVATIVES AS INHIBITORS OF PLASMA KALLIKREIN KALVISTA PHARMACEUTICALS LIMITED (GB) 2013-01-10 WO claimed
CN-101475541-B Preparation of 4-methyl thiazole-5-carboxyl acid HATAI KE YANGZHOU MATERIALS CO LTD 2011-05-25 CN claimed