SCHEMBL18623536

SCHEMBL18623536

N#Cc1ccc(-n2c3ccccc3c3cc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)ccc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PGR P06401 1/20 0.42
PTGER4 P35408 2/20 0.42
USP14 P54578 2/20 0.40
PIK3CD O00329 1/20 0.40
PIK3CA P42336 1/20 0.40
RORC P51449 6/20 0.40
HDAC4 P56524 1/20 0.39
MAP4K4 O95819 1/20 0.38
KIF11 P52732 1/20 0.38
TNKS O95271 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18623540 1.00 KDM4E (0.46) KDM4EATML3MBTL1PGRPTGER4
SCHEMBL15250620 1.00 KDM4E (0.46) KDM4EATML3MBTL1PGRPTGER4
SCHEMBL15250632 1.00 KDM4E (0.46) KDM4EATML3MBTL1PGRPTGER4
SCHEMBL17772248 0.98 KDM4E (0.47) KDM4EATML3MBTL1PGRPTGER4
SCHEMBL29511674 0.98 KDM4E (0.47) KDM4EATML3MBTL1PGRPTGER4
SCHEMBL23071695 0.97 KDM4E (0.47) KDM4EATML3MBTL1PGRPTGER4
SCHEMBL21984907 0.97 KDM4E (0.47) KDM4EATML3MBTL1PGRPTGER4
SCHEMBL21984918 0.97 KDM4E (0.47) KDM4EATML3MBTL1PGRPTGER4
SCHEMBL15248304 0.97 KDM4E (0.51) KDM4EATML3MBTL1PGRPTGER4
SCHEMBL18779597 0.97 KDM4E (0.47) KDM4EATML3MBTL1PGRPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210210697-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-07-08 US disclosed
US-20170207396-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-20 US disclosed
US-20170207396-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-20 US disclosed
US-20170077423-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-03-16 US disclosed
US-20170077423-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-03-16 US disclosed