Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17169108 | 0.84 | KCNN4 (0.33) | KCNN4 | |
| SCHEMBL15704705 | 0.78 | KCNN4 (0.33) | KCNN4 | |
| SCHEMBL18623890 | 0.76 | PDE2A (0.33) | — | |
| SCHEMBL17118625 | 0.71 | KCNN4 (0.31) | KCNN4 | |
| SCHEMBL15902934 | 0.71 | KCNN4 (0.30) | KCNN4 | |
| SCHEMBL15904331 | 0.69 | KCNN4 (0.35) | KCNN4 | |
| SCHEMBL15904435 | 0.69 | KCNN4 (0.35) | KCNN4 | |
| SCHEMBL12450813 | 0.67 | CYP3A4 (0.30) | — | |
| SCHEMBL3674130 | 0.66 | KCNN4 (0.42) | ALDH1A1KCNN4 | |
| SCHEMBL1239429 | 0.66 | KCNN4 (0.42) | ALDH1A1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073337-A1 | DIHYDROTHIAZINE AND DIHYDROOXAZINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073337-A1 | DIHYDROTHIAZINE AND DIHYDROOXAZINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | BACE1, BACE2, APP | ALDH1A1 1285/4885GAA 707/4885KCNN4 2937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.