⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25701106 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL29088682 | 0.78 | — | — | |
| SCHEMBL22570009 | 0.78 | CYP2D6 (0.44) | — | |
| SCHEMBL14901030 | 0.76 | — | — | |
| SCHEMBL13831243 | 0.74 | CYP2D6 (0.46) | — | |
| SCHEMBL21884806 | 0.74 | — | — | |
| SCHEMBL22019223 | 0.74 | — | — | |
| SCHEMBL366427 | 0.74 | CYP2D6 (0.52) | — | |
| SCHEMBL25975594 | 0.74 | — | — | |
| SCHEMBL24529778 | 0.72 | CYP2D6 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |
| EP-2890374-B1 | COMPOSITIONS AND METHODS FOR DRUG-SENSITIZATION OR INHIBITION OF A CANCER CELL | TEXAS A & M UNIV SYS (US) | 2019-04-03 | — | — | EP | disclosed |
| US-9867807-B2 | Compositions and methods for drug-sensitization or inhibition of a cancer cell | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-01-16 | — | — | US | disclosed |
| US-9867807-B2 | Compositions and methods for drug-sensitization or inhibition of a cancer cell | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-01-16 | — | — | US | disclosed |
| US-9765087-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2017-09-19 | — | — | US | disclosed |
| EP-2341140-B1 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION AS (DK) | 2017-07-19 | — | — | EP | disclosed |
| US-20170114046-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARM INC (US) | 2017-04-27 | — | — | US | disclosed |
| US-20170071905-A1 | COMPOSITIONS AND METHODS FOR DRUG-SENSITIZATION OR INHIBITION OF A CANCER CELL | THE TEXAS A&M UNIVERSITY SYSTEM | 2017-03-16 | — | — | US | disclosed |
| US-20170071905-A1 | COMPOSITIONS AND METHODS FOR DRUG-SENSITIZATION OR INHIBITION OF A CANCER CELL | THE TEXAS A&M UNIVERSITY SYSTEM | 2017-03-16 | — | — | US | disclosed |