Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 19/20 | 0.55 |
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16930478 | 0.93 | MME (0.62) | MMEACEMMEL1 | |
| SCHEMBL20306265 | 0.89 | MME (0.52) | MMEMMEL1 | |
| SCHEMBL20306264 | 0.88 | MME (0.54) | MMEACEMMEL1 | |
| SCHEMBL16930646 | 0.87 | MME (0.61) | MMEACEMMEL1 | |
| SCHEMBL18626456 | 0.86 | MME (0.53) | MMEACEMMEL1 | |
| SCHEMBL16940998 | 0.85 | MME (0.76) | MMEMMEL1 | |
| SCHEMBL16930500 | 0.84 | MME (0.54) | MMEMMEL1 | |
| SCHEMBL16930533 | 0.84 | MME (0.54) | MMEACEMMEL1 | |
| SCHEMBL16930647 | 0.83 | MME (0.55) | MMEMMEL1 | |
| SCHEMBL20099619 | 0.82 | MME (0.48) | MMEACEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593110-B2 | Neprilysin inhibitors | Theravence Biopharma R&D IP, LLC (US) | 2017-03-14 | — | — | US | disclosed |