SCHEMBL18626454

SCHEMBL18626454

CCOC(=O)[C@H](CCN)C[C@@H](Cc1ccc(-c2cc(Cl)ccc2F)cc1)NC(=O)c1c[nH]nn1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16930693 0.94 MME (0.65) MME
SCHEMBL18874689 0.94 MME (0.65) MME
SCHEMBL20306294 0.90 MME (0.74) MME
SCHEMBL20099597 0.90 MME (0.57) MME
SCHEMBL20306320 0.90 MME (0.59) MME
SCHEMBL16930516 0.90 MME (0.76) MME
SCHEMBL16975181 0.90 MME (0.76) MME
SCHEMBL16941473 0.89 MME (0.77) MME
SCHEMBL20099601 0.89 MME (0.62) MME
SCHEMBL16930585 0.89 MME (0.59) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593110-B2 Neprilysin inhibitors Theravence Biopharma R&D IP, LLC (US) 2017-03-14 — — US disclosed
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