Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 20/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16939330 | 0.92 | MME (0.52) | MMEACE | |
| SCHEMBL18626466 | 0.92 | MME (0.55) | MMEACE | |
| SCHEMBL20099595 | 0.91 | MME (0.56) | MMEACE | |
| SCHEMBL16939296 | 0.86 | MME (0.52) | MMEACE | |
| SCHEMBL18874713 | 0.85 | MME (0.51) | MMEACE | |
| SCHEMBL16939261 | 0.84 | MME (0.55) | MMEACE | |
| SCHEMBL20306310 | 0.84 | MME (0.54) | MMEACE | |
| SCHEMBL16930430 | 0.84 | MME (0.57) | MMEACE | |
| SCHEMBL16975147 | 0.84 | MME (0.57) | MMEACE | |
| SCHEMBL16930542 | 0.84 | MME (0.57) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593110-B2 | Neprilysin inhibitors | Theravence Biopharma R&D IP, LLC (US) | 2017-03-14 | — | — | US | disclosed |