Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442635 | 0.94 | MEN1 (0.47) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL3978516 | 0.81 | MAPT (0.42) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL1066368 | 0.80 | F10 (0.49) | MEN1KMT2ANPSR1CYP3A4ATM | |
| SCHEMBL16214712 | 0.80 | F10 (0.49) | MEN1KMT2ANPSR1CYP3A4ATM | |
| SCHEMBL16391282 | 0.80 | F10 (0.49) | MEN1KMT2ANPSR1CYP3A4ATM | |
| SCHEMBL27639337 | 0.79 | MAPT (0.41) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL27207556 | 0.78 | MAPT (0.41) | MEN1KMT2APOLBMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL5528439 | 0.78 | MAPT (0.41) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL6916576 | 0.78 | MAPT (0.41) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL16407822 | 0.78 | F10 (0.42) | POLBNPSR1PAX8TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141252-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Inc. (US) | 2017-03-15 | — | — | EP | disclosed |