Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.45 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18632984 | 0.84 | EGFR (0.64) | EGFRERBB4KDREPHB4 | |
| SCHEMBL15090597 | 0.77 | EGFR (0.71) | EGFREPHA2KDREPHB4 | |
| SCHEMBL18633107 | 0.75 | EGFR (0.46) | EGFRERBB4ALDH1A1MAPT | |
| SCHEMBL18633103 | 0.72 | EGFR (0.42) | EGFR | |
| SCHEMBL18632975 | 0.71 | EGFR (0.52) | EGFRERBB4EPHA2KDREPHB4 | |
| SCHEMBL15090622 | 0.66 | EGFR (0.70) | EGFREPHA2KDREPHB4 | |
| SCHEMBL15090694 | 0.66 | EGFR (0.59) | EGFR | |
| SCHEMBL22914712 | 0.66 | KDM4E (0.41) | EGFRERBB4ALDH1A1MAPT | |
| SCHEMBL24585190 | 0.65 | MAPT (0.36) | EGFRKDREPHB4ALDH1A1MAPT | |
| SCHEMBL15090717 | 0.65 | EGFR (0.73) | EGFRERBB4EPHA2KDREPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612860-B1 | QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF | XUANZHU PHARMA CO LTD (CN) | 2017-03-15 | — | — | EP | disclosed |