Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.48 |
| ▸ | FBP1 | P09467 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18632977 | 0.91 | ABCG2 (0.54) | EGFRFBP1ABCG2ALK | |
| SCHEMBL18862789 | 0.88 | EGFR (0.63) | EGFRFBP1ABCG2 | |
| SCHEMBL30237488 | 0.84 | EGFR (0.63) | EGFRFBP1 | |
| SCHEMBL29615011 | 0.84 | EGFR (0.63) | EGFRFBP1 | |
| SCHEMBL25241 | 0.84 | EGFR (0.63) | EGFRFBP1 | |
| Hydrochloric Acid SCHEMBL4780920 | 0.83 | EGFR (0.62) | EGFRFBP1 | |
| SCHEMBL14387983 | 0.82 | EGFR (0.48) | EGFR | |
| SCHEMBL4579486 | 0.81 | EGFR (0.56) | EGFRFBP1ABCG2ALK | |
| SCHEMBL28413582 | 0.81 | EGFR (0.59) | EGFRFBP1ABCG2 | |
| SCHEMBL14388259 | 0.81 | EIF2AK2 (0.44) | EGFRFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612860-B1 | QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF | XUANZHU PHARMA CO LTD (CN) | 2017-03-15 | — | — | EP | disclosed |