Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.70 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.53 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15090806 | 0.90 | EGFR (0.85) | EGFRERBB2ERBB4 | |
| SCHEMBL18633090 | 0.90 | EGFR (0.85) | EGFRERBB2ERBB4 | |
| SCHEMBL10029549 | 0.90 | EGFR (0.85) | EGFRERBB2ERBB4 | |
| SCHEMBL15105075 | 0.90 | EGFR (0.85) | EGFRERBB2ERBB4 | |
| SCHEMBL15100141 | 0.85 | EGFR (0.72) | EGFRERBB2ERBB4 | |
| SCHEMBL15112830 | 0.84 | EGFR (0.83) | EGFRERBB2ERBB4 | |
| SCHEMBL15104579 | 0.82 | EGFR (1.00) | EGFRERBB2ERBB4 | |
| SCHEMBL15090473 | 0.82 | EGFR (1.00) | EGFRERBB2ERBB4 | |
| SCHEMBL15104577 | 0.82 | EGFR (1.00) | EGFRERBB2ERBB4 | |
| SCHEMBL15112797 | 0.82 | EGFR (0.80) | EGFRERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612860-B1 | QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF | XUANZHU PHARMA CO LTD (CN) | 2017-03-15 | — | — | EP | disclosed |