Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13824505 | 0.75 | CCR1 (0.32) | CCR1TBXA2RHRH1 | |
| SCHEMBL15478326 | 0.72 | CCR1 (0.58) | CCR1TBXA2RHRH1 | |
| SCHEMBL18633703 | 0.71 | CCR1 (0.32) | CCR1TBXA2RHRH1HRH3 | |
| SCHEMBL18895974 | 0.69 | CCR1 (0.38) | CCR1TBXA2RHRH1 | |
| SCHEMBL18896008 | 0.69 | HRH3 (0.31) | HRH3 | |
| SCHEMBL15478382 | 0.69 | HRH1 (0.34) | CCR1HRH1 | |
| SCHEMBL14579593 | 0.68 | TBXA2R (0.31) | CCR1TBXA2RHRH1 | |
| SCHEMBL16312668 | 0.67 | CCR1 (0.39) | CCR1HRH1HRH3 | |
| SCHEMBL18633827 | 0.66 | CCR1 (0.39) | CCR1HRH1HRH3 | |
| SCHEMBL13824458 | 0.66 | CCR1 (0.37) | CCR1HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688418-B1 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARM INC (US) | 2017-03-15 | — | — | EP | disclosed |