Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13824447 | 0.93 | CCR1 (0.39) | CCR1CARM1PRMT6 | |
| SCHEMBL18896010 | 0.93 | CCR1 (0.39) | CCR1CARM1PRMT6 | |
| SCHEMBL18633827 | 0.82 | CCR1 (0.39) | CCR1 | |
| SCHEMBL13824459 | 0.81 | CCR1 (0.40) | CCR1 | |
| SCHEMBL13617089 | 0.77 | TBXA2R (0.31) | CCR1 | |
| SCHEMBL14579593 | 0.77 | TBXA2R (0.31) | CCR1 | |
| SCHEMBL18633820 | 0.77 | CCR1 (0.37) | CCR1 | |
| SCHEMBL18633836 | 0.76 | CCR1 (0.33) | CCR1 | |
| SCHEMBL14420045 | 0.76 | CCR1 (0.40) | CCR1 | |
| SCHEMBL18896011 | 0.76 | CCR1 (0.37) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688418-B1 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARM INC (US) | 2017-03-15 | — | — | EP | disclosed |