Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10309336 | 0.85 | PDE10A (0.52) | PDE10A | |
| SCHEMBL10309348 | 0.79 | PDE10A (0.54) | PDE10A | |
| SCHEMBL10309447 | 0.74 | PDE10A (0.70) | PDE10A | |
| SCHEMBL10309354 | 0.73 | PDE10A (0.52) | PDE10A | |
| SCHEMBL18634454 | 0.71 | PDE10A (0.47) | PDE10A | |
| SCHEMBL18634565 | 0.69 | PDE10A (0.66) | PDE10A | |
| SCHEMBL19965860 | 0.68 | PDE10A (0.48) | PDE10A | |
| SCHEMBL10309340 | 0.64 | PDE10A (0.59) | PDE10A | |
| SCHEMBL12066224 | 0.63 | PDE10A (0.63) | PDE10A | |
| SCHEMBL10309383 | 0.62 | PDE10A (0.63) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210984-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2019-06-19 | — | — | EP | disclosed |
| EP-3210984-A1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-2663565-B1 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2017-03-15 | — | — | EP | disclosed |