Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.90 |
| ▸ | CA4 | P22748 | 4/20 | 0.61 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28661921 | 1.00 | CA1 (0.90) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL8906449 | 1.00 | CA1 (0.90) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL28311516 | 0.95 | CA1 (0.82) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL28206729 | 0.95 | CA1 (0.82) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL28188112 | 0.95 | CA1 (0.82) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL8411866 | 0.95 | CA1 (0.82) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL153505 | 0.95 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL1964006 | 0.95 | CA1 (1.00) | CA1CA4FAHD1LMNAFFAR3 | |
| Acetic Acid SCHEMBL1332530 | 0.95 | — | — | |
| Acetic Acid SCHEMBL2289 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116973358-A | Detection reagent for sulfides in water and preparation method thereof | 洛阳莱博图电子科技有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-113984688-A | Sulfide detection device based on gas-phase molecules and use method | 浙江浙能技术研究院有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-109932215-B | Interstitial hydrosulfide sampling device and method | 浙江省海洋水产研究所 | 2021-08-20 | — | — | CN | claimed |
| CN-110987844-A | Method for detecting sulfide content in textile clothes | 佛山中纺联检验技术服务有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-109932215-A | A kind of Interstitial Water sulfide sampler and method | 浙江省海洋水产研究所 | 2019-06-25 | — | — | CN | claimed |
| CN-207516255-U | A kind of sulfide is acidified air blowing instrument | 沈阳和盛昌科技有限公司 | 2018-06-19 | — | — | CN | claimed |
| CN-107389581-A | A kind of discrete method for testing sulfide concentration | 苏州北裕环保仪器制造有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-107290494-A | A kind of water quality sample-leaving system, method and water quality monitoring system | 力合科技（湖南）股份有限公司 | 2017-10-24 | — | — | CN | claimed |
| CN-102565262-B | Determination method for hydrogen sulfide in mainstream smoke of cigarette | CHINA TOBACCO JIANGSU IND CO | 2014-01-22 | — | — | CN | claimed |
| CN-103499540-A | Measurement method for hydrogen sulfide content of methanol solution and application of measurement method | SHENHUA GROUP CORP LTD | 2014-01-08 | — | — | CN | claimed |
| CN-102565262-A | Determination method for hydrogen sulfide in mainstream smoke of cigarette | CHINA TOBACCO JIANGSU IND CO | 2012-07-11 | — | — | CN | claimed |
| CN-220794781-U | Sulfide acidification blowing instrument | 宁波瑞起检测技术有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-116477772-B | Method for removing chromium and desulfurizing bacillus cereus in water and application thereof | 盐城工学院 | 2023-11-14 | — | — | CN | disclosed |
| CN-116973358-A | Detection reagent for sulfides in water and preparation method thereof | 洛阳莱博图电子科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116973358-A | Detection reagent for sulfides in water and preparation method thereof | 洛阳莱博图电子科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-102565262-A | Determination method for hydrogen sulfide in mainstream smoke of cigarette | CHINA TOBACCO JIANGSU IND CO | 2012-07-11 | — | — | CN | disclosed |
| CN-101551367-B | Low pressure ion-exclusion chromatography for synchronously analyzing chloride and sulphide | SICHUAN UNIVERSITY (CN) | 2012-02-08 | — | — | CN | disclosed |
| US-7939334-B2 | Simultaneous analysis of chlorides and sulfides by low pressure ion exclusion chromatography | SICHUAN UNIVERSITY (CN) | 2011-05-10 | — | — | US | disclosed |
| US-20100267159-A1 | SIMULTANEOUS ANALYSIS OF CHLORIDES AND SULFIDES BY LOW PRESSURE ION EXCLUSION CHROMATOGRAPHY | SICHUAN UNIVERSITY (CN) | 2010-10-21 | — | — | US | disclosed |
| CN-101551367-A | Low pressure ion-exclusion chromatography for synchronously analyzing chloride and sulphide | UNIV SICHUAN (CN) | 2009-10-07 | — | — | CN | disclosed |