Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 6/20 | 0.47 |
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.33 |
| ▸ | TSPO | P30536 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1866815 | 1.00 | TLR4 (0.47) | TLR4MRGPRX1TSPOHRH1METAP2 | |
| SCHEMBL1865568 | 1.00 | TLR4 (0.47) | TLR4MRGPRX1TSPOHRH1METAP2 | |
| SCHEMBL1870179 | 1.00 | TLR4 (0.47) | TLR4MRGPRX1TSPOHRH1METAP2 | |
| SCHEMBL1864627 | 1.00 | TLR4 (0.47) | TLR4MRGPRX1TSPOHRH1METAP2 | |
| SCHEMBL1863864 | 1.00 | TLR4 (0.47) | TLR4MRGPRX1TSPOHRH1METAP2 | |
| SCHEMBL1865684 | 1.00 | TLR4 (0.47) | TLR4MRGPRX1TSPOHRH1METAP2 | |
| SCHEMBL1865150 | 1.00 | TLR4 (0.47) | TLR4MRGPRX1TSPOHRH1METAP2 | |
| SCHEMBL1864233 | 1.00 | TLR4 (0.47) | TLR4MRGPRX1TSPOHRH1METAP2 | |
| SCHEMBL1864118 | 1.00 | TLR4 (0.47) | TLR4MRGPRX1TSPOHRH1METAP2 | |
| SCHEMBL1866031 | 1.00 | TLR4 (0.47) | TLR4MRGPRX1TSPOHRH1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935835-B2 | Substituted cycloalkene derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-05-03 | — | — | US | disclosed |