SCHEMBL186419

SCHEMBL186419

C=CN1CCCC1=O.CC=C(C)C(N)=O

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
LMNA P02545 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
BRD4 O60885 1/20 0.32
BRD2 P25440 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetamide SCHEMBL28242549 0.89 TSHR (0.42) TSHRLMNACA12CA1CA2
SCHEMBL6304602 0.87 TDP1 (0.40) TSHRLMNACA12CA1CA2
SCHEMBL34237 0.86 KMT2A (0.34) TSHRLMNACA12CA1CA2
SCHEMBL5292575 0.86 KMT2A (0.34) TSHRLMNACA12CA1CA2
Urea SCHEMBL27484938 0.85 TSHR (0.44) TSHRLMNACA12CA1CA2
Acrylamide SCHEMBL6025647 0.84 TSHR (0.39) TSHRLMNACA12CA1CA2
Acetic Acid SCHEMBL887070 0.83 BRD4 (0.39) TSHRLMNACA12CA1CA2
Acrylamide SCHEMBL7158303 0.83 TDP1 (0.36) TSHRLMNACA12CA1CA2
Acrylamide SCHEMBL18066844 0.82 TSHR (0.42) TSHRLMNACA12CA1CA2
Acrylamide SCHEMBL1162173 0.82 TSHR (0.42) TSHRLMNACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2118155-B1 CATIONIC COPOLYMERS DERIVED FROM ACRYLAMIDES AND USE THEREOF SPCM SA (FR) 2014-11-05 EP claimed
EP-1838923-B1 METHOD OF PRODUCING HIGH DRY STRENGTH PAPER AND CARDBOARD AND PAPER AND CARDBOARD THUS OBTAINED SPCM SA (FR) 2012-01-04 EP claimed
EP-2118155-A2 CATIONIC COPOLYMERS DERIVED FROM ACRYLAMIDES AND USE THEREOF SNF SAS (FR) 2009-11-18 EP claimed
WO-2008113934-A2 CATIONIC COPOLYMERS DERIVED FROM ACRYLAMIDES AND USE THEREOF SNF S.A.S. (FR) 2008-09-25 WO claimed
EP-1838923-A2 METHOD OF PRODUCING HIGH DRY STRENGTH PAPER AND CARDBOARD AND PAPER AND CARDBOARD THUS OBTAINED SNF S.A.S. (FR) 2007-10-03 EP claimed
WO-2006075115-A2 METHOD OF PRODUCING HIGH DRY STRENGTH PAPER AND CARDBOARD AND PAPER AND CARDBOARD THUS OBTAINED SNF S.A.S. (FR) 2006-07-20 WO claimed
US-5010141-A Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed
US-6211280-B1 AQUEOUS SOLUTION OF POLYURETHANE AND (METH)ACRYLIC ACID PPG INDUSTRIES OHIO, INC. 2001-04-03 US disclosed
US-5824413-A POLYURETHANE AND POLYACRYLIC ACID PPG INDUSTRIES, INC. (US) 1998-10-20 US disclosed