Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 8/20 | 0.66 |
| ▸ | CCNA2 | P20248 | 12/20 | 0.54 |
| ▸ | CDK2 | P24941 | 12/20 | 0.54 |
| ▸ | CCNA1 | P78396 | 12/20 | 0.54 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18642905 | 0.95 | RET (0.66) | RETCCNA2CDK2CCNA1LCK | |
| SCHEMBL18642791 | 0.81 | RET (0.64) | RETLCKSRC | |
| SCHEMBL18642792 | 0.81 | RET (0.63) | RETLCKSRC | |
| SCHEMBL19732739 | 0.80 | RET (1.00) | RET | |
| SCHEMBL19732746 | 0.80 | RET (1.00) | RETLCKSRC | |
| SCHEMBL18642903 | 0.78 | RET (0.66) | RETCCNA2CDK2CCNA1LCK | |
| SCHEMBL18642794 | 0.78 | RET (0.66) | RETLCKSRC | |
| SCHEMBL18643070 | 0.78 | RET (0.65) | RETLCKSRC | |
| SCHEMBL18642937 | 0.78 | RET (0.62) | RETCCNA2CDK2CCNA1LCK | |
| SCHEMBL19732785 | 0.78 | RET (0.96) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017043550-A1 | CONDENSED PYRIMIDINE COMPOUND OR SALT THEREOF | 大鵬薬品工業株式会社 | 2017-03-16 | — | — | WO | disclosed |