⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22481534 | 1.00 | — | — | |
| SCHEMBL14222480 | 1.00 | — | — | |
| SCHEMBL4757565 | 0.76 | — | — | |
| SCHEMBL18394704 | 0.76 | — | — | |
| SCHEMBL21275990 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL25287315 | 0.74 | — | — | |
| SCHEMBL8802483 | 0.74 | SLC6A2 (0.43) | — | |
| SCHEMBL5028765 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL22532128 | 0.73 | SLC6A2 (0.42) | — | |
| SCHEMBL22532098 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021097061-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2021-05-20 | — | — | WO | disclosed |
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |
| EP-2739615-B1 | PHENYL-3-AZA-BICYCLO[3.1.0]HEX-3-YL-METHANONES AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM INT (DE) | 2017-03-15 | — | — | EP | disclosed |