SCHEMBL186435

SCHEMBL186435

Fc1ccc(CCl)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Magnesium SCHEMBL29786468 0.97 IDO1 (0.50)
SCHEMBL467320 0.97 IDO1 (0.50)
Phosphine SCHEMBL5512746 0.97 IDO1 (0.50)
SCHEMBL852177 0.97 IDO1 (0.50)
Hydrochloric Acid SCHEMBL28502839 0.97 IDO1 (0.50)
SCHEMBL2990337 0.92 TAAR1 (0.54)
SCHEMBL27864115 0.92 IDO1 (0.46)
SCHEMBL1725688 0.92 MAOB (0.52)
SCHEMBL10564566 0.92 IDO1 (0.46)
(Chloromethyl)Benzene SCHEMBL11209021 0.89 PLA2G1B (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2763 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912847-A Composite coating and application thereof 万华化学集团股份有限公司 2025-05-02 CN claimed
CN-116947791-B Furanamide antitumor compound and preparation method and application thereof 北京中医药大学 2025-04-25 CN claimed
CN-119060019-A Quinazolines heterocyclic compound for ship antifouling and preparation method thereof 净峰科技(舟山)有限公司 2024-12-03 CN claimed
CN-118852047-A Preparation method of mosapride citrate intermediate and preparation method of mosapride citrate 吉林修正药业新药开发有限公司 2024-10-29 CN claimed
CN-118666932-A Cholesterol oxime ester/oxime ether derivative, preparation method and application 西北农林科技大学 2024-09-20 CN claimed
US-12060375-B2 Method for the dehydrogenation of dichlorosilane WACKER CHEMIE AG (DE) 2024-08-13 US claimed
CN-221433071-U Device for preparing p-fluorobenzaldehyde by hydrolyzing p-fluorobenzyl chloride 浙江大洋生物科技集团股份有限公司 2024-07-30 CN claimed
CN-118146068-A Method for preparing (substituted) benzyl alcohol/aldehyde by rapid phase transfer hydrolysis of benzyl chloride 南京工业大学 2024-06-07 CN claimed
CN-112638921-B Method for the dehydrogenation of dichlorosilane 瓦克化学股份公司 2024-05-14 CN claimed
CN-117884060-A System for preparing p-fluorobenzaldehyde by hydrolyzing p-fluorobenzyl chloride 浙江大洋生物科技集团股份有限公司 2024-04-16 CN claimed
US-20070037938-A1 Using a catalyst system including: a manganese carbonyl radical initiator (dimanganese decacarbonyl); a halogen containing reactive substrate; and an allylic halogen substituted chain termination agent (2,3-dibromopropene) to produce telechelic polymers with narrow molecular weight distribution IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2007-02-15 US claimed
EP-1606323-A1 POLYMERISATION OF ETHYLENICALLY UNSATURATED MONOMERS Imperial Chemical Industries PLC (GB) 2005-12-21 EP claimed
WO-2004085494-A1 POLYMERISATION OF ETHYLENICALLY UNSATURATED MONOMERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 2004-10-07 WO claimed
EP-0150036-A1 Azolyl-aryl-alkanole-derivatives, processes for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1985-07-31 EP claimed
US-4450298-A Vapor phase catalytic hydrolysis of benzal chloride or its halogen- or trifluoromethyl-substitute to form benzaldehyde or substitute CENTRAL GLASS COMPANY, LIMITED (JP) 1984-05-22 US claimed
EP-0034430-B1 PROCESS FOR PREPARING ARYLACETALDEHYDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-05 EP claimed
US-4338467-A IN THE PRESENCE OF A COBALT CATALYST AND A NITRILE SOLVENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-07-06 US claimed
EP-0034430-A1 Process for preparing arylacetaldehydes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-08-26 EP claimed
US-4248779-A REACTING CARBONYL SULFIDE WITH A SECONDARY AMINE AND REACTING THE AMINE SALT WITH A HALOHYDROCARBON IHARA CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 1981-02-03 US claimed
US-4152352-A PRODUCTION OF ARYLPYRUVIC ACIDS RHONE-POULENC INDUSTRIES (FR) 1979-05-01 US claimed