⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868510 | 1.00 | — | — | |
| SCHEMBL1864577 | 1.00 | — | — | |
| SCHEMBL5966226 | 0.98 | POLB (0.36) | — | |
| SCHEMBL20295933 | 0.92 | — | — | |
| SCHEMBL360829 | 0.92 | — | — | |
| SCHEMBL20295697 | 0.92 | — | — | |
| SCHEMBL5966260 | 0.84 | — | — | |
| SCHEMBL5482159 | 0.81 | POLB (0.34) | — | |
| SCHEMBL11384229 | 0.79 | KDM4E (0.34) | — | |
| SCHEMBL11384206 | 0.79 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 567 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117983302-A | Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof | 华东理工大学 | 2024-05-07 | — | — | CN | claimed |
| US-20230122243-A1 | Heteroaromatic inhibitors of astacin proteinases | VIVORYON THERAPEUTICS N.V. (DE) | 2023-04-20 | — | — | US | claimed |
| CN-114585608-A | Heteroaromatic inhibitors of astacin protease | 维沃永治疗公众有限公司 | 2022-06-03 | — | — | CN | claimed |
| EP-3986868-A1 | HETEROAROMATIC INHIBITORS OF ASTACIN PROTEINASES | Vivoryon Therapeutics N.V. (DE) | 2022-04-27 | — | — | EP | claimed |
| WO-2020249760-A1 | HETEROAROMATIC INHIBITORS OF ASTACIN PROTEINASES | VIVORYON THERAPEUTICS AG (DE) | 2020-12-17 | — | — | WO | claimed |
| US-20170189443-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS | PLATINUM MONTAUR LIFE SCIENCES, LLC AND AS AGENT (KY) | 2017-07-06 | — | — | US | claimed |
| CN-106456662-A | Compositions of pentosan polysulfate for oral administration and methods of use thereof | 奥利金制药公司 | 2017-02-22 | — | — | CN | claimed |
| EP-3110427-A1 | COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE | Urigen Pharmaceuticals, Inc. (US) | 2017-01-04 | — | — | EP | claimed |
| WO-2015127416-A1 | COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE | URIGEN PHARMACEUTICALS, INC. (US) | 2015-08-27 | — | — | WO | claimed |
| US-20130150323-A1 | USE OF ORAL HEPARIN PREPARATIONS TO TREAT URINARY TRACT DISEASES AND CONDITIONS | Urigen Pharmaceuticals, Inc (US) | 2013-06-13 | — | — | US | claimed |
| WO-2005113582-A1 | SUBSTITUTED ETHANE-1,2-DIAMINES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-01 | — | — | WO | claimed |
| CN-1190893-A | Compounds and compositions for delivery of active agents | EMISPHERE TECH INC (US) | 1998-08-19 | — | — | CN | claimed |
| EP-0654995-B1 | 4-OXA-1-AZABICYCLO (3,2,0) HEPTAN-7-ONE DERIVATIVES AS ANTITUMOR AGENTS | TAIHO PHARMACEUTICAL CO LTD (JP) | 1996-10-23 | — | — | EP | claimed |
| US-5561126-A | OXAPENAMS HAVING CHEMICAL STABILITY; ANTICARCINOGENIC AGENTS; LEUKEMIA | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-10-01 | — | — | US | claimed |
| EP-0654995-A1 | 4-OXA-1-AZABICYCLO (3,2,0) HEPTAN-7-ONE DERIVATIVES AS ANTITUMOR AGENTS. | TAIHO PHARMACEUTICAL CO LTD (JP) | 1995-05-31 | — | — | EP | claimed |
| US-5362559-A | Improved strength and uniformity | KABUSHIKI KAISHA TOSHIBA (JP) | 1994-11-08 | — | — | US | claimed |
| CN-1082548-A | Antineoplastic agent 4-oxa--1-azabicyclo [3,2, O] heptane-7-ketone derivatives | MEDICINE BIOLOG TECH I CHINA M (CN) | 1994-02-23 | — | — | CN | claimed |
| WO-1994001109-A1 | 4-OXA-1-AZABICYCLO [3,2,0] HEPTAN-7-ONE DERIVATIVES AS ANTITUMOR AGENTS | TAIHO PHARMACEUTICAL CO. LTD. (JP) | 1994-01-20 | — | — | WO | claimed |
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | claimed |
| CN-1046893-A | PROCESS FOR PREPARATION OF 2-CYCLOHEXYL CARBOXYLATES | RHONE POULENC CHIMIE (FR) | 1990-11-14 | — | — | CN | claimed |