SCHEMBL18645808

SCHEMBL18645808

C=C(C)C(=O)OCCCc1cc(-c2ccc(-c3ccc(-c4ccc(CCCCC)cc4)cc3)cc2CC)ccc1OCCC(CC)(CO)CO

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 5/20 0.36
CNR2 P34972 2/20 0.36
CNR1 P21554 1/20 0.36
HTT P42858 3/20 0.35
MAPT P10636 3/20 0.35
MAPK1 P28482 2/20 0.35
APAF1 O14727 2/20 0.35
THRB P10828 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
RAD52 P43351 2/20 0.35
NPC1 O15118 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TSHR P16473 2/20 0.34
PTPN1 P18031 1/20 0.34
PTPN6 P29350 1/20 0.34
PTPN11 Q06124 1/20 0.34
RARB P10826 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17070502 1.00 S1PR1 (0.36) S1PR1CNR2CNR1HTTMAPT
SCHEMBL18646510 0.99 CNR2 (0.36) S1PR1CNR2CNR1HTTMAPT
SCHEMBL18647066 0.96 S1PR1 (0.37) S1PR1CNR2CNR1HTTMAPT
SCHEMBL17070362 0.96 S1PR1 (0.37) S1PR1CNR2CNR1HTTMAPT
SCHEMBL18645619 0.96 S1PR1 (0.40) S1PR1CNR2CNR1HTTMAPT
SCHEMBL17070500 0.95 CNR2 (0.36) S1PR1CNR2CNR1HTTMAPT
SCHEMBL18645809 0.95 CNR2 (0.36) S1PR1CNR2CNR1HTTMAPT
SCHEMBL18645803 0.95 CNR2 (0.36) S1PR1CNR2CNR1HTTMAPT
SCHEMBL17070509 0.95 CNR2 (0.36) S1PR1CNR2CNR1HTTMAPT
SCHEMBL18646487 0.95 CNR2 (0.37) S1PR1CNR2CNR1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265344-A1 POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM MERCK PATENT GMBH (DE) 2023-08-24 US disclosed
US-20230265344-A1 POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM MERCK PATENT GMBH (DE) 2023-08-24 US disclosed
US-11214736-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2022-01-04 US disclosed
US-20180171231-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-06-21 US disclosed
US-20180171231-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-06-21 US disclosed
WO-2017041893-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-03-16 WO disclosed