SCHEMBL18645819

SCHEMBL18645819

c1ccc(N(c2ccc(-c3ccc4cc5c(cc4c3)sc3ccccc35)cc2)c2ccc(C3(c4ccccc4)c4ccccc4-c4ccccc43)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
OPRK1 P41145 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20348971 0.94 MAPT (0.32) MAPTKDM4EMEN1LMNAOPRK1
SCHEMBL20348958 0.93 MAPT (0.33) MAPTKDM4EMEN1LMNAOPRK1
SCHEMBL20349035 0.91
SCHEMBL23353573 0.91 MAPT (0.32) MAPTKDM4EMEN1LMNAOPRK1
SCHEMBL17126582 0.91 S1PR5 (0.33) MAPTKDM4EMEN1LMNAOPRK1
SCHEMBL16631186 0.90 S1PR5 (0.33) MAPTKDM4EMEN1LMNAOPRK1
SCHEMBL16631102 0.90 S1PR5 (0.33) MAPTKDM4EMEN1LMNAOPRK1
SCHEMBL18326022 0.90 PIM3 (0.33) MAPTKDM4EMEN1LMNAOPRK1
SCHEMBL17126510 0.90 S1PR5 (0.33) MAPTKDM4EMEN1LMNAOPRK1
SCHEMBL17804598 0.89 MEN1 (0.35) MAPTKDM4EMEN1LMNAOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11673875-B2 Organic compound, organic optoelectric diode, and display device SAMSUNG SDI CO., LTD. (KR) 2023-06-13 US disclosed
US-11673875-B2 Organic compound, organic optoelectric diode, and display device SAMSUNG SDI CO., LTD. (KR) 2023-06-13 US disclosed
US-20180186764-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRIC DIODE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-07-05 US disclosed
US-20180186764-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRIC DIODE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-07-05 US disclosed
WO-2017043757-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2017-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11673875-B2 Organic compound, organic optoelectric diode, and display device OXER1, OCIAD1, OR10J3 MAPT 1938/4885KDM4E 3502/4885MEN1 2869/4885
US-20180186764-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRIC DIODE, AND DISPLAY DEVICE OXER1, OCIAD1, OR10J3 MAPT 1938/4885KDM4E 3502/4885MEN1 2869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.