Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18646363 | 0.89 | CHRM1 (0.63) | CHRM1 | |
| SCHEMBL20979770 | 0.89 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL18645651 | 0.89 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL18646266 | 0.89 | CHRM1 (0.80) | CHRM1 | |
| SCHEMBL20481663 | 0.88 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL20481675 | 0.85 | CHRM1 (0.81) | CHRM1 | |
| SCHEMBL17924305 | 0.84 | CHRM1 (0.77) | CHRM1 | |
| SCHEMBL16610136 | 0.83 | CHRM1 (0.76) | CHRM1 | |
| SCHEMBL16610131 | 0.83 | CHRM1 (0.76) | CHRM1 | |
| SCHEMBL16610088 | 0.83 | CHRM1 (0.77) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347349-B1 | FLUOROINDOLE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2019-09-18 | — | — | EP | claimed |
| US-10294217-B2 | Fluoroindole derivatives as muscarinic M1 receptor positive allosteric modulators | SUVEN LIFE SCIENCES LIMITED (IN) | 2019-05-21 | — | — | US | claimed |
| US-20180244655-A1 | Fluoroindole Derivatives as Muscarinic M1 Receptor Positive Allosteric Modulators | SUVEN LIFE SCIENCES LIMITED (IN) | 2018-08-30 | — | — | US | claimed |
| EP-3347349-B1 | FLUOROINDOLE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2019-09-18 | — | — | EP | disclosed |
| EP-3347349-B1 | FLUOROINDOLE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2019-09-18 | — | — | EP | disclosed |
| US-10294217-B2 | Fluoroindole derivatives as muscarinic M1 receptor positive allosteric modulators | SUVEN LIFE SCIENCES LIMITED (IN) | 2019-05-21 | — | — | US | disclosed |
| US-10294217-B2 | Fluoroindole derivatives as muscarinic M1 receptor positive allosteric modulators | SUVEN LIFE SCIENCES LIMITED (IN) | 2019-05-21 | — | — | US | disclosed |
| US-20180244655-A1 | Fluoroindole Derivatives as Muscarinic M1 Receptor Positive Allosteric Modulators | SUVEN LIFE SCIENCES LIMITED (IN) | 2018-08-30 | — | — | US | disclosed |
| WO-2017042643-A1 | FLUOROINDOLE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LIMITED (IN) | 2017-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294217-B2 | Fluoroindole derivatives as muscarinic M1 receptor positive allosteric modulators | CHRM1, CHRM2, CHRM3 | CHRM1 1/4885 |
| US-20180244655-A1 | Fluoroindole Derivatives as Muscarinic M1 Receptor Positive Allosteric Modulators | CHRM1, CHRM2, CHRM3 | CHRM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.