Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18588864 | 0.89 | KMT2A (0.53) | KMT2AACACBALPLALPIALPG | |
| SCHEMBL18603451 | 0.88 | KMT2A (0.69) | KMT2ANPC1RAB9A | |
| SCHEMBL13073495 | 0.87 | KMT2A (0.58) | KMT2AMMP8OPRM1 | |
| SCHEMBL16254367 | 0.87 | KMT2A (0.58) | KMT2AMMP8OPRM1 | |
| SCHEMBL18647234 | 0.83 | MME (0.55) | KMT2A | |
| SCHEMBL18608747 | 0.81 | TSHR (0.63) | KMT2ARAB9APPARG | |
| SCHEMBL25101089 | 0.79 | POLB (0.53) | KMT2AACACBNPC1RAB9APPARG | |
| SCHEMBL20862301 | 0.79 | POLB (0.53) | KMT2AACACBNPC1RAB9APPARG | |
| SCHEMBL22111634 | 0.79 | POLB (0.53) | KMT2AACACBNPC1RAB9APPARG | |
| SCHEMBL22880671 | 0.79 | TSHR (0.55) | MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017044584-A1 | PSMA-TARGETED NIR DYES AND THEIR USES | On Target Laboratories, LLC (US) | 2017-03-16 | — | — | WO | disclosed |