Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17194061 | 1.00 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL17184133 | 1.00 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL26453244 | 0.90 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL18648079 | 0.90 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL16481662 | 0.90 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL17184148 | 0.89 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL17194062 | 0.89 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL17184180 | 0.88 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL16481549 | 0.88 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL17194055 | 0.87 | IRAK4 (1.00) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598440-B2 | Inhibitors of IRAK4 activity | MERCK SHARP & DOHME CORP. (US) | 2017-03-21 | — | — | US | disclosed |