Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 20/20 | 0.78 |
| ▸ | CSNK1D | P48730 | 11/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16708846 | 0.93 | CSNK1E (0.87) | CSNK1ECSNK1D | |
| SCHEMBL16699598 | 0.93 | CSNK1E (0.86) | CSNK1ECSNK1D | |
| SCHEMBL16730840 | 0.90 | CSNK1E (0.73) | CSNK1ECSNK1D | |
| SCHEMBL16708843 | 0.90 | CSNK1E (0.81) | CSNK1ECSNK1D | |
| SCHEMBL18648758 | 0.89 | CSNK1E (0.68) | CSNK1ECSNK1D | |
| SCHEMBL16700222 | 0.89 | CSNK1E (0.76) | CSNK1ECSNK1D | |
| SCHEMBL16700891 | 0.88 | CSNK1E (0.73) | CSNK1ECSNK1D | |
| SCHEMBL16708816 | 0.88 | CSNK1E (1.00) | CSNK1ECSNK1D | |
| SCHEMBL16699352 | 0.88 | CSNK1E (0.80) | CSNK1ECSNK1D | |
| SCHEMBL16708822 | 0.87 | CSNK1E (0.77) | CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598423-B2 | Substituted 4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazine derivatives as casein kinase 1 D/E inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-21 | — | — | US | disclosed |