Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 17/20 | 0.61 |
| ▸ | CSNK1D | P48730 | 10/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18648706 | 0.90 | CSNK1E (0.59) | CSNK1ECSNK1D | |
| SCHEMBL18171238 | 0.89 | CSNK1E (0.65) | CSNK1ECSNK1D | |
| SCHEMBL16728661 | 0.89 | CSNK1E (0.75) | CSNK1ECSNK1D | |
| SCHEMBL16728635 | 0.89 | CSNK1E (0.70) | CSNK1ECSNK1D | |
| SCHEMBL16728664 | 0.88 | CSNK1E (0.60) | CSNK1ECSNK1D | |
| SCHEMBL18648758 | 0.86 | CSNK1E (0.68) | CSNK1ECSNK1D | |
| SCHEMBL16708809 | 0.85 | CSNK1E (0.82) | CSNK1ECSNK1D | |
| SCHEMBL16728668 | 0.85 | CSNK1E (0.57) | CSNK1ECSNK1D | |
| SCHEMBL18183982 | 0.85 | CSNK1E (0.61) | CSNK1ECSNK1D | |
| SCHEMBL16728749 | 0.84 | CSNK1E (0.66) | CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598423-B2 | Substituted 4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazine derivatives as casein kinase 1 D/E inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-03-21 | — | — | US | disclosed |