Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | PTGES | O14684 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16998542 | 0.93 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAMEN1NPC1GALR3 | |
| SCHEMBL16998543 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAMEN1NPC1GALR3 | |
| SCHEMBL16998550 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAMEN1NPC1GALR3 | |
| SCHEMBL16998544 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMEN1NPC1GALR3 | |
| SCHEMBL16998539 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMEN1NPC1GALR3 | |
| SCHEMBL16998541 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMEN1NPC1GALR3 | |
| SCHEMBL16901883 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAMEN1NPC1GALR3 | |
| SCHEMBL16998545 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAMEN1NPC1GALR3 | |
| SCHEMBL25955362 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAMEN1NPC1GALR3 | |
| SCHEMBL18672267 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAMEN1NPC1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598399-B2 | Compound suitable for detection of mitochondrial complex-1 | HAMAMATSU PHOTONICS K.K. (JP) | 2017-03-21 | — | — | US | disclosed |