Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 12/20 | 0.96 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24067253 | 1.00 | EPHX1 (0.96) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18650000 | 1.00 | EPHX1 (0.96) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19729051 | 1.00 | EPHX1 (0.96) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20365873 | 1.00 | EPHX1 (0.96) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20365870 | 1.00 | EPHX1 (0.96) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1824180 | 0.98 | EPHX1 (1.00) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20528277 | 0.98 | EPHX1 (1.00) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22669919 | 0.98 | EPHX1 (1.00) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24067211 | 0.98 | EPHX1 (1.00) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20528278 | 0.98 | EPHX1 (1.00) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317235-A1 | METHODS AND SYSTEMS FOR POLYMER PRECIPITATION AND GENERATION OF PARTICLES | NOVARTIS AG (CH) | 2021-10-14 | — | — | US | disclosed |
| US-20170362346-A1 | METHODS AND SYSTEMS FOR POLYMER PRECIPITATION AND GENERATION OF PARTICLES | CERULEAN PHARMA INC (US) | 2017-12-21 | — | — | US | disclosed |
| US-9598503-B2 | Methods and systems for polymer precipitation and generation of particles | CERULEAN PHARMA INC. (US) | 2017-03-21 | — | — | US | disclosed |