SCHEMBL18652525

SCHEMBL18652525

C[C@H](C1CCC[C@@H]1P(c1ccccc1)c1ccccc1)P(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6264929 1.00 GAA (0.31) GAAL3MBTL1RECQL
SCHEMBL6264931 1.00 GAA (0.31) GAAL3MBTL1RECQL
Cyclopentane SCHEMBL30958867 0.97 KDM4E (0.30)
SCHEMBL17696314 0.90
SCHEMBL16449946 0.90
SCHEMBL23742008 0.90
SCHEMBL13150731 0.86 KCNA5 (0.33) GAAL3MBTL1RECQL
SCHEMBL6265198 0.86
SCHEMBL6390335 0.86
SCHEMBL6390108 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11577233-B2 Monocarbonyl ruthenium and osmium catalysts Universita' Delgi Studi Di Udine (IT) 2023-02-14 US disclosed
US-20220168720-A1 MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS UNIV DEGLI STUDI UDINE (IT) 2022-06-02 US disclosed
US-20210107929-A1 DICARBONYL RUTHENIUM AND OSMIUM CATALYSTS UNIVERSITA' DEGLI STUDI DI UDINE AND INNOVATION FACTORY S.R.L. (IT) 2021-04-15 US disclosed
EP-3411347-B1 MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS UNIV DEGLI STUDI UDINE (IT) 2021-03-31 EP disclosed
US-10301337-B2 Process JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2019-05-28 US disclosed
US-20180170954-A1 Process JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2018-06-21 US disclosed
US-9932362-B2 Processes for the preparation of ruthenium or osmium complexes comprising P and N donor ligands JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2018-04-03 US disclosed
WO-2017134620-A1 DICARBONYL RUTHENIUM AND OSMIUM CATALYSTS UNIVERSITA' DEGLI STUDI DI UDINE (IT) 2017-08-10 WO disclosed
WO-2017134618-A1 MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS UNIVERSITA' DEGLI STUDI DI UDINE (IT) 2017-08-10 WO disclosed
US-20170081350-A1 PROCESSES FOR THE PREPARATION OF RUTHENIUM OR OSMIUM COMPLEXES COMPRISING P AND N DONOR LIGANDS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2017-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10301337-B2 Process OSTC, EXOSC9, OGA GAA 3865/4885L3MBTL1 4701/4885RECQL 2842/4885
US-20170081350-A1 PROCESSES FOR THE PREPARATION OF RUTHENIUM OR OSMIUM COMPLEXES COMPRISING P AND N DONOR LIGANDS OSTC, POP1, OGA GAA 4704/4885L3MBTL1 4487/4885RECQL 1158/4885
US-20220168720-A1 MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS OTC, CBR3, IDH2 GAA 4525/4885L3MBTL1 3237/4885RECQL 3518/4885
US-20210107929-A1 DICARBONYL RUTHENIUM AND OSMIUM CATALYSTS OTC, ODC1, CBR3 GAA 4061/4885L3MBTL1 2973/4885RECQL 1408/4885
US-20180170954-A1 Process OSTC, EXOSC9, OGA GAA 3865/4885L3MBTL1 4701/4885RECQL 2842/4885
US-11577233-B2 Monocarbonyl ruthenium and osmium catalysts OTC, CBR3, IDH2 GAA 4525/4885L3MBTL1 3237/4885RECQL 3518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.