Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | CDC7 | O00311 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241603 | 1.00 | SCN10A (0.61) | SCN10AALDH1A1LMNAMAPTHTT | |
| SCHEMBL2756437 | 0.83 | SCN10A (0.61) | SCN10AALDH1A1LMNAMAPTHTT | |
| SCHEMBL1592503 | 0.83 | SCN10A (0.61) | SCN10AALDH1A1LMNAMAPTHTT | |
| SCHEMBL3265964 | 0.83 | SCN10A (0.61) | SCN10AALDH1A1LMNAMAPTHTT | |
| SCHEMBL240766 | 0.83 | SCN10A (0.71) | SCN10AALDH1A1LMNAMAPTHTT | |
| SCHEMBL1592500 | 0.83 | SCN10A (0.61) | SCN10AALDH1A1LMNAMAPTHTT | |
| SCHEMBL239964 | 0.82 | SCN10A (0.43) | SCN10ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL239486 | 0.82 | SCN10A (0.53) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL2275135 | 0.82 | SCN10A (0.53) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL240231 | 0.82 | SCN10A (0.53) | SCN10APARP1CDC7CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-B1 | ANTI-VIRAL COMPOUNDS | ABBVIE BAHAMAS LTD (BS) | 2017-03-22 | — | — | EP | disclosed |