⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15254172 | 1.00 | ODC1 (0.45) | — | |
| SCHEMBL15254562 | 1.00 | ODC1 (0.45) | — | |
| SCHEMBL15254439 | 1.00 | ODC1 (0.45) | — | |
| SCHEMBL15254005 | 1.00 | ODC1 (0.45) | — | |
| SCHEMBL15254213 | 1.00 | ODC1 (0.45) | — | |
| SCHEMBL15253912 | 1.00 | ODC1 (0.45) | — | |
| SCHEMBL15254361 | 1.00 | ODC1 (0.45) | — | |
| SCHEMBL15254591 | 1.00 | ODC1 (0.45) | — | |
| SCHEMBL15254169 | 1.00 | ODC1 (0.45) | — | |
| SCHEMBL2466589 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323344-A1 | POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER | ARES CAPITAL CORPORATION, AS AGENT | 2023-10-12 | — | — | US | disclosed |
| EP-4101930-A1 | POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION | ModernaTX, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| EP-3350333-B1 | POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION | MODERNATX INC (US) | 2021-10-27 | — | — | EP | disclosed |
| US-20190078087-A1 | POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER | ARES CAPITAL CORPORATION, AS AGENT | 2019-03-14 | — | — | US | disclosed |
| WO-2017049275-A2 | POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION | MODERNA THERAPEUTICS, INC. (US) | 2017-03-23 | — | — | WO | disclosed |
| WO-2017049286-A1 | POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER | MODERNA THERAPEUTICS, INC. (US) | 2017-03-23 | — | — | WO | disclosed |