Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21415446 | 0.95 | TSHR (0.64) | TSHRCNR1EPHX2SLC6A5LPAR1 | |
| SCHEMBL13347916 | 0.89 | CNR1 (0.60) | TSHRCNR1EPHX2LPAR1LPAR2 | |
| SCHEMBL14262301 | 0.87 | TSHR (0.81) | TSHRCNR1HPGDMEN1KMT2A | |
| SCHEMBL17776037 | 0.87 | EPHX2 (0.56) | CNR1EPHX2SLC6A5LPAR1HPGD | |
| SCHEMBL21554118 | 0.86 | TSHR (0.56) | TSHRCNR1EPHX2SLC6A5LPAR1 | |
| SCHEMBL18653591 | 0.84 | EPHX2 (0.46) | TSHRCNR1EPHX2SLC6A5LPAR1 | |
| SCHEMBL18736125 | 0.84 | EPHX2 (0.72) | CNR1EPHX2SLC6A5LPAR1LPAR2 | |
| SCHEMBL10311846 | 0.83 | TSHR (0.59) | TSHRCNR1LPAR1LPAR2ENPP2 | |
| SCHEMBL17154348 | 0.83 | TSHR (0.51) | TSHRCNR1EPHX2LPAR1LPAR2 | |
| SCHEMBL18973140 | 0.83 | EPHX2 (0.51) | CNR1EPHX2SLC6A5LPAR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3228651-A1 | A METHOD FOR PREPARING POLYESTERAMIDES BY ORGANIC CATALYSIS | Nanjing Tech University (CN) | 2017-10-11 | — | — | EP | disclosed |
| US-20170081475-A1 | METHOD FOR PREPARING PLOYESTERAMIDES BY ORGANIC CATALIYSIS | NANJING TECH UNIVERSITY (CN) | 2017-03-23 | — | — | US | disclosed |