Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.53 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.53 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.53 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275434 | 0.98 | KDM4E (0.60) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL28008265 | 0.97 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL28371003 | 0.97 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL27761606 | 0.97 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL28210406 | 0.97 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL28575933 | 0.97 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL28366897 | 0.97 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL31396225 | 0.97 | KDM4E (0.59) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL3505902 | 0.93 | KDM4E (0.67) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL14359917 | 0.92 | KDM4E (0.55) | KDM4EMEN1RECQLKMT2APOLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120302487-A1 | COMPOSITE | REVOLYMER LIMITED (GB) | 2012-11-29 | — | — | US | claimed |
| EP-2494024-A1 | COMPOSITE | Revolymer Limited (GB) | 2012-09-05 | — | — | EP | claimed |
| WO-2011051681-A1 | COMPOSITE | REVOLYMER LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| US-20140171327-A1 | NOVEL COMPOSITE | REVOLYMER (U.K.) LIMITED (GB) | 2014-06-19 | — | — | US | disclosed |
| EP-2697355-A1 | PARTICLES WITH HYDROXYL VINYLIC COPOLYMER COATING SENSITIVE TO IONIC STRENGTH | Revolymer Limited (GB) | 2014-02-19 | — | — | EP | disclosed |
| US-20120302487-A1 | COMPOSITE | REVOLYMER LIMITED (GB) | 2012-11-29 | — | — | US | disclosed |
| WO-2012140442-A1 | PARTICLES WITH HYDROXYL VINYLIC COPOLYMER COATING SENSITIVE TO IONIC STRENGTH | REVOLYMER LIMITED (GB) | 2012-10-18 | — | — | WO | disclosed |
| EP-2494024-A1 | COMPOSITE | Revolymer Limited (GB) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051681-A1 | COMPOSITE | REVOLYMER LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171327-A1 | NOVEL COMPOSITE | PUF60, C5, VCL | KDM4E 291/4885MEN1 3035/4885RECQL 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.