SCHEMBL18656133

SCHEMBL18656133

Cc1ccc(-c2cc(NC(=O)c3ccc(Oc4cc5c(cc4C)C(C(=O)O)CCO5)cc3)ccc2F)cc1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1570352 0.87 PTGDR2 (1.00) PTGDR2
SCHEMBL18656083 0.81 PTGDR2 (0.59) PTGDR2
SCHEMBL1570252 0.80 PTGDR2 (0.82) PTGDR2
SCHEMBL1569850 0.77 PTGDR2 (1.00) PTGDR2
SCHEMBL15949571 0.76 PTGDR2 (0.80) PTGDR2
SCHEMBL13273404 0.75 NPC1 (0.56) PTGDR2
SCHEMBL1569654 0.74 PTGDR2 (1.00) PTGDR2
SCHEMBL1569502 0.73 PTGDR2 (1.00) PTGDR2
SCHEMBL1569645 0.73 PTGDR2 (1.00) PTGDR2
SCHEMBL1570306 0.73 PTGDR2 (0.75) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3144303-A1 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES Array Biopharma, Inc. (US) 2017-03-22 EP disclosed