SCHEMBL18656141

SCHEMBL18656141

CNC(=O)C1CCOc2cc(Oc3ccc(C(=O)NC4Cc5ccccc5C4)cc3)c(C#N)cc21

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1569745 0.91 PTGDR2 (0.85) PTGDR2
SCHEMBL1571213 0.91 PTGDR2 (1.00) PTGDR2
SCHEMBL13574679 0.89 PTGDR2 (0.88) PTGDR2
SCHEMBL1571463 0.87 PTGDR2 (0.85) PTGDR2
SCHEMBL1570418 0.87 PTGDR2 (1.00) PTGDR2
SCHEMBL15949681 0.85 PTGDR2 (0.79) PTGDR2
SCHEMBL1569940 0.84 PTGDR2 (0.86) PTGDR2
SCHEMBL1569643 0.84 PTGDR2 (1.00) PTGDR2
SCHEMBL1571132 0.83 PTGDR2 (1.00) PTGDR2
SCHEMBL1569580 0.81 PTGDR2 (1.00) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3144303-A1 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES Array Biopharma, Inc. (US) 2017-03-22 EP disclosed