Beta-2'-C-Methyl-6-O-Methyl Guanosine

Beta-2'-C-Methyl-6-O-Methyl Guanosine

SCHEMBL18656235

COc1nc(N)nc2c1ncn2[C@@H]1OC(CO)[C@@H](O)[C@@]1(C)O

nearest known ligand 0.66

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 9/20 0.66
ADA P00813 1/20 0.58
ADORA3 P0DMS8 10/20 0.53
ADORA1 P30542 7/20 0.53
ADORA2B P29275 5/20 0.53
ALOX15 P16050 1/20 0.53
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL15618029 1.00 ADORA2A (0.66) ADORA2AADAADORA3ADORA1ADORA2B
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL12194676 1.00 ADORA2A (0.66) ADORA2AADAADORA3ADORA1ADORA2B
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL721333 1.00 ADORA2A (0.66) ADORA2AADAADORA3ADORA1ADORA2B
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL15628197 1.00 ADORA2A (0.66) ADORA2AADAADORA3ADORA1ADORA2B
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL19493379 1.00 ADORA2A (0.66) ADORA2AADAADORA3ADORA1ADORA2B
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL14762374 1.00 ADORA2A (0.66) ADORA2AADAADORA3ADORA1ADORA2B
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL12219172 1.00 ADORA2A (0.66) ADORA2AADAADORA3ADORA1ADORA2B
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL12939406 1.00 ADORA2A (0.66) ADORA2AADAADORA3ADORA1ADORA2B
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL14816756 1.00 ADORA2A (0.66) ADORA2AADAADORA3ADORA1ADORA2B
Beta-2'-C-Methyl-6-O-Methyl Guanosine SCHEMBL30230607 1.00 ADORA2A (0.66) ADORA2AADAADORA3ADORA1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2909223-B1 DINUCLEOTIDE COMPOUNDS FOR HCV INFECTION IDENIX PHARMACEUTICALS LLC (US) 2017-03-22 EP disclosed