Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.85 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | FLT3 | P36888 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 10/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 5/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylapigenin SCHEMBL29350875 | 0.92 | ABCB1 (1.00) | ABCB1MEN1KMT2AALDH1A1KDM4E | |
| Trimethylapigenin SCHEMBL1421585 | 0.92 | ABCB1 (1.00) | ABCB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17193739 | 0.85 | ABCB1 (0.87) | ABCB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL20100895 | 0.85 | ABCB1 (0.82) | ABCB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4279323 | 0.84 | ABCB1 (0.80) | ABCB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29978577 | 0.83 | ABCB1 (0.82) | ABCB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17185527 | 0.83 | ABCB1 (0.82) | ABCB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL311530 | 0.83 | ABCB1 (0.82) | ABCB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22667395 | 0.83 | ABCB1 (0.82) | ABCB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28280309 | 0.83 | ABCB1 (0.82) | ABCB1MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2902399-B1 | Water-soluble derivatives and prodrugs of acacetin and methods of making and using thereof | VERSITECH LTD (CN) | 2017-03-22 | — | — | EP | disclosed |